Funding for UC San Diego’s Center for Computational Biology & Bioinformatics is provided by the following sources:
UC San Diego Health Sciences: UC San Diego Health Sciences encompasses the School of Medicine, the Skaggs School of Pharmacy and Pharmaceutical Sciences, and UC San Diego Health System, including UC San Diego Medical Center, in Hillcrest; and in La Jolla, Thornton Hospital, Moores Cancer Center, Sulpizio Cardiovascular Center; and other centers, primary and specialty practices of the UC San Diego Medical Group faculty physicians. As a top-tier academic medical center, its role is to provide leadership in improving health through research, education and patient care.
CTRI Center for Accelerating Drug Development (CADD) – Grant UL1TR001442
The UC San Diego Clinical and Translational Research Institute (CTRI) Center for Accelerating Drug Development (CADD) integrates our biomarker laboratory, computational biology, and phase I unit to facilitate novel early stage clinical trials. The CADD brings together three key elements of early drug development: the CTRI Biomarker Laboratory; the CTRI Phase I Unit; and the Center for Computational Biology and Bioinformatics (CCBB). The biomarker lab designs and validates assays; the phase I unit and project management team execute the study; and the biomarker lab performs assays on the biosamples. The CCBB assists with analysis of data generated by the Biomarker Laboratory and other omics technologies, and correlates with clinical and laboratory data from the research participants.
The Center for Microbiome Innovation – UC San Diego is a world-leader in microbiome research, biomedical engineering, quantitative measurements and modeling, cellular and chemical imaging, drug discovery, “omics” sciences and much more. We draw interdisciplinary teams of these researchers together to push the boundaries of human understanding of microbiomes — the distinct constellations of bacteria, viruses and other microorganisms that live within and around humans, other species and the environment.
Psychiatric Cell Mapping Initiative – The mission of the Psychiatric Cell Map Initiative (PCMI) is to bridge the gap between the genome and clinic in the field of neuropsychiatric disorder research by systematically mapping the physical and genetic interaction networks underlying these disorders, including autism spectrum disorders, Tourette disorder, epilepsy, intellectual disability, and schizophrenia.
Past funding sources:
San Diego Center for Systems Biology (SDCSB) – Grant P50GM085764
The mission of the San Diego Center for Systems Biology is to advance the discipline and application of systems biology in the greater San Diego area and to serve as a nucleus for systems biology education and training. The SDCSB brings together a community of 19 outstanding faculty, over 100 trainees and technical staff spanning four world-renowned institutions: the University of California San Diego, the Salk Institute for Biological Studies, the Sanford-Burnham Medical Research Institute and the Ludwig Institute for Cancer Research, all located on the Torrey Pines research mesa.
National Resource for Network Biology (NRNB) – Grant P41GM103504
The aim of the National Resource for Network Biology (NRNB) is to advance the new science of Biological Networks through analytic tools, visualizations, databases and computing resources. Biomedical research is increasingly dependent on knowledge of biological networks of multiple types and scales, including gene, protein and drug interactions, cell-cell and cell-host communication, and vast social networks. Our technologies enable researchers to assemble and analyze these networks and to use them to better understand biological systems and, in particular, how they fail in disease. NRNB leverages the Cytoscape Cyberinfrastructure, a widely-used network analysis platform which we further support through a rich set of tutorials, workshops, 24/7 help desk assistance, and over 100 collaboration and service projects.
Moores Cancer Center (MCC) – Grant P30CA023100
Moores Cancer Center is one of just 41 National Cancer Institute-designated Comprehensive Cancer Centers in the United States, and the only one in the San Diego region. Such centers are prominent among the leading institutions in the nation dedicated to scientific innovation and clinical excellence, and studies show that outcomes are better at NCI-designated centers. We are unique in bringing clinical care together with support services, clinical trials, prevention and outreach programs, and cancer research laboratories — all under one roof.
The San Diego Digestive Diseases Research Center (SDDRC) draws on the ever-expanding biomedical research enterprise in the San Diego area, and the opportunity to select a unique subset of academic investigators for Center membership, whose work complements the thematic focus of the Center on “Inflammation in the Digestive Tract.” Center investigators conduct outstanding research related to inflammation, immunity, and host-microbial interactions in both gastrointestinal tract and liver. Topics range from basic mechanisms governing inflammation, the role of infection, immune and inflammatory responses in preclinical studies, to translational studies and clinical trials with human tissues and well-defined patient populations.
Diabetes Research Center – The overall mission of the UCSD-UCLA DRC is to foster research in the prevention and treatment of diabetes and its complications, and to improve the lives of patients suffering from this devastating disease.